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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FLT4
All Species:
23.03
Human Site:
S1250
Identified Species:
50.67
UniProt:
P35916
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35916
NP_002011.2
1298
145599
S1250
G
A
E
T
R
G
S
S
R
M
K
T
F
E
E
Chimpanzee
Pan troglodytes
XP_518160
1359
151684
S1246
G
A
E
T
R
G
S
S
R
M
K
T
F
E
E
Rhesus Macaque
Macaca mulatta
XP_001107118
1294
145144
S1181
G
T
Q
T
H
G
S
S
R
M
K
T
F
E
E
Dog
Lupus familis
XP_538585
1362
152583
S1249
G
T
Q
T
Q
G
P
S
R
M
K
T
F
E
E
Cat
Felis silvestris
Mouse
Mus musculus
P35917
1363
152998
S1250
G
T
K
T
P
G
S
S
R
M
K
T
F
E
E
Rat
Rattus norvegicus
Q91ZT1
1363
153298
S1250
G
T
K
A
P
G
S
S
R
M
K
T
F
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517468
812
91764
E765
Y
K
D
E
K
L
V
E
E
V
S
G
I
D
L
Chicken
Gallus gallus
Q8QHL3
1327
149408
K1253
R
F
T
W
T
G
S
K
Q
K
W
T
L
F
G
Frog
Xenopus laevis
Q91909
954
106841
M907
T
F
K
Q
I
V
Q
M
V
E
Q
Q
L
S
D
Zebra Danio
Brachydanio rerio
Q5MD89
1357
153159
S1246
G
P
S
S
T
C
H
S
R
V
K
T
F
E
E
Tiger Blowfish
Takifugu rubipres
P79750
975
110895
I928
Q
D
E
Q
E
K
L
I
Y
R
N
V
Q
P
E
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.5
91.7
85
N.A.
84.4
84.3
N.A.
42.5
41.3
25.9
52
27.1
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
91.6
92.9
88.9
N.A.
88.6
88.1
N.A.
50.4
58.7
42.9
67.4
43.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
80
73.3
N.A.
80
73.3
N.A.
0
20
0
53.3
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
86.6
86.6
N.A.
86.6
80
N.A.
26.6
26.6
20
66.6
13.3
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
0
10
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
10
0
0
0
0
0
0
0
0
0
0
10
10
% D
% Glu:
0
0
28
10
10
0
0
10
10
10
0
0
0
64
73
% E
% Phe:
0
19
0
0
0
0
0
0
0
0
0
0
64
10
0
% F
% Gly:
64
0
0
0
0
64
0
0
0
0
0
10
0
0
10
% G
% His:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
10
0
0
0
0
10
0
0
% I
% Lys:
0
10
28
0
10
10
0
10
0
10
64
0
0
0
0
% K
% Leu:
0
0
0
0
0
10
10
0
0
0
0
0
19
0
10
% L
% Met:
0
0
0
0
0
0
0
10
0
55
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
10
0
0
19
0
10
0
0
0
0
0
0
10
0
% P
% Gln:
10
0
19
19
10
0
10
0
10
0
10
10
10
0
0
% Q
% Arg:
10
0
0
0
19
0
0
0
64
10
0
0
0
0
0
% R
% Ser:
0
0
10
10
0
0
55
64
0
0
10
0
0
10
0
% S
% Thr:
10
37
10
46
19
0
0
0
0
0
0
73
0
0
0
% T
% Val:
0
0
0
0
0
10
10
0
10
19
0
10
0
0
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _